The IIFA Best Villain Award is chosen via a worldwide poll and the winner is announced at the ceremony.
The winners are listed below:-
| Year | Actor/Actress | Film |
|---|---|---|
| 2000 | Naseeruddin Shah | Sarfarosh |
| 2001 | Sushant Singh | Jungle |
| 2002 | Akshay Kumar | Ajnabee |
| 2003 | Akshaye Khanna | Humraaz |
| 2004 | Feroz Khan | Janasheen |
| 2005 | John Abraham | Dhoom |
| 2006 | Nana Patekar | Apaharan |
| 2007 | Saif Ali Khan | Omkara |
| 2008 | Vivek Oberoi | Shootout at Lokhandwala |
| 2009 | Akshaye Khanna | Race |
| 2010 | Boman Irani | 3 Idiots |
| 2011 | Sonu Sood | Dabangg |